“…Preliminary data indicates that cannabis use had a stronger effect on the memory functions of male students than female students. Both sexes were however, equally affected by cannabis on inhibitory control.”
“”Adolescence is associated with the maturation of cognitive functions, such as working memory, decision-making, and impulsivity control. This is a highly vulnerable period for the development of the brain as it represents a critical period wherein regulatory connection between higher-order regions of the cortex and emotional processing circuits deeper inside the brain are established. It is a period of strong remodeling, making adolescents highly vulnerable to drug-related developmental disturbances.”
– substance use to be linked to low cognitive functioning, a finding that could be indicative of an underlying common vulnerability.
– Cannabis use was linked to impairments in working memory and inhibitory control, which is required for self-control.
– Cannabis use was also linked to deficits in memory recall and perceptual reasoning.
– Alcohol use was not linked to impairments in these cognitive functions, suggesting cannabis could have more long-term effects than alcohol.”
the primary psychoactive component of cannabis, delta-9-tetrahydrocannabinol or THC, on the adolescent brain, in rodent animal models. His team demonstrated that:
– adolescent exposure to THC induces changes in specific a region of the brain called the prefrontal cortex (PFC)
– and in a brain circuit, the mesolimbic pathway, that closely resemble the abnormalities observed in schizophrenia.
– Furthermore, adolescent THC exposure also caused affective and cognitive abnormalities including deficits in social interactions, memory processing and anxiety regulation.