“…significantly more DNA sequence repeats in patients with schizophrenia than in control individuals, and outline a possible link between genome instability and disease.”

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“Patients with clinically important CNVs showed a range of characteristics, such as developmental problems and refusal to accept treatment,” first author Itaru Kushima says. “And, the presence of two CNVs resulted in a more severe phenotype.” Continue reading

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“The environment leaves traces on the brain, on organs and also on gametes. Through gametes, these traces can be passed to the next generation.”

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Recent Findings on Trauma

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Childhood trauma, and especially neglect, mainly before second grade and for girls, seems the basis for most adult medical problems and self-harming behaviors.  So, let’s keep up on the latest research, here are some findings:

“In individuals with a genetic predisposition, trauma causes long-term changes in DNA methylation leading to a lasting dysregulation of the stress hormone system. As a result, those affected find themselves less able to cope with stressful situations throughout their lives, frequently leading to depression, post-traumatic stress disorder or anxiety disorders in adulthood.”

Epigenetic dysregulation of the glucocorticoid receptor gene is reversible Continue reading

“The mediocrity principle is the idea that because we are not in any special location in the universe, we should not be anything special in the universe.”

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“We are on the third planet around a tediously boring star surrounded by other completely normal stars about two-thirds of the way along one of several arms of a remarkably average spiral galaxy.”

“Heritability describes the extent to which phenotypic differences between individuals can be explained by genetic differences in a particular population with that population’s mix of genetic and environmental influences at that time. “

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