Few things on this research area:
- There is some evidence that all mental illnesses sit along a continuum of similar inherited/genetic neuronal malfunctions that are similar in cause and effect. One friend, an expert in this field, said she suspected all mental illnesses were ‘just” different configurations of similar, hyper-frequent, milliesecond neuronal seizures.
- There is an idea that all mental illnesses are a variation on schizophrenia. Yipee! (BMM)
Children At Risk For Mental Disorders Experience Communication Breakdown In Brain Networks Supporting Attention
Attention deficits are central to psychiatric disorders such as schizophrenia or bipolar disorder, and are thought to precede the presentation of the illnesses. A new study suggests that the brain network interactions between regions that support attention are dysfunctional in children and adolescents at genetic risk for developing schizophrenia and bipolar disorder.
Attention deficits are central to psychiatric disorders such as schizophrenia or bipolar disorder, and are thought to precede the presentation of the illnesses. A new study …suggests that the brain network interactions between regions that support attention are dysfunctional in children and adolescents at genetic risk for developing schizophrenia and bipolar disorder.
“The brain network mechanisms that mediate these deficits are poorly understood, and have rarely been tackled using complex image analytic methods that focus on how brain regions communicate,”
The study is clinically significant because the estimated lifetime incidence of schizophrenia or bipolar disorder in the groups studied is approximately 10-20 times what is generally observed. “We believe that genetic risk may confer vulnerability for dysfunctional brain network communication. This abnormal network communication in turn might amplify risk for psychiatric illnesses. By identifying markers of network dysfunction we believe we can elucidate these mechanisms of risk. This knowledge may in turn increase focus on possible premeditative intervention strategies,”
The study indicates that brain networks supporting basic psychological functions such as attention do not communicate appropriately in young individuals at genetic risk for illnesses such as schizophrenia or bipolar disorder.
“Genetics and neurodevelopment are inextricably linked. How psychiatric illnesses emerge from their combination is a central question in medicine. Analytic tools developed in the last few years offer the promise of answers at the level of how these processes impact brain network communication,”