Dopamine Is “Seeking” Neurotransmitter Not the “Reward” N-transmitter

Standard

Previously, dopamine in the ventral portion of the striatum  was considered to be the “pleasure” neurotransmitter involved in the action of all abused drugs.  However, clinical findings suggest that drugs that block the dopamine receptor do not block methamphetamine “liking.” The dopamine story continues to evolve, with dopamine now viewed by some as a chemical involved in the motivational “wanting” aspect of drug-taking behaviour.*

Salamone JD, Correa M, Farra A, et al. Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits. Psychopharmacology (Berl) 2007;191:461-82.
Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s